Literature Selection / Selezione della Letteratura

• Suter TM et al.: "Trastuzumab-associated cardiac adverse effects in the herceptin adjuvant trial", J Clin Oncol. 2007 Sep 1;25(25):3859-65
• Pinder MC et al.: "Congestive heart failure in older women treated with adjuvant anthracycline chemotherapy for breast cancer", J Clin Oncol. 2007 Sep 1;25(25):3808-15
• Jacobsen PB et al.: "Fatigue after treatment for early stage breast cancer: a controlled comparison", Cancer. 2007 Sep 10; [Epub ahead of print]
• Killander F et al.: "Radiotherapy and tamoxifen after mastectomy in postmenopausal women - 20 year follow-up of the South Sweden Breast Cancer group randomised trial SSBCG II:I.
  Eur J Cancer. 2007 Sep;43(14):2100-8
• Polgar C et al.: "Breast-conserving treatment with partial or whole breast irradiation for low-risk invasive breast carcinoma-5-year results of a randomized trial", Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):694-702
• Yau TK et al.: "Evaluation of the prognostic value of 2005 St Gallen risk categories for operated breast cancers in Hong Kong", Breast. 2007 Sep 3; [Epub ahead of print]
• Groenvold M et al.: "Psychological distress and fatigue predicted recurrence and survival in primary breast cancer patients", Breast Cancer Res Treat. 2007 Oct;105(2):209-19
• Cleveland RJ et al.: "Weight gain prior to diagnosis and survival from breast cancer", Cancer Epidemiol Biomarkers Prev. 2007 Sep;16(9):1803-11
• Moller P et al.: "Surveillance for familial breast cancer: Differences in outcome according to BRCA mutation status", Int J Cancer. 2007 Sep 1;121(5):1017-20
• Graves KD et al.: "Predictors and outcomes of contralateral prophylactic mastectomy among breast cancer survivors", Breast Cancer Res Treat. 2007 Sep;104(3):321-9
• Hartman M et al.: "Incidence and prognosis of synchronous and metachronous bilateral breast cancer", J Clin Oncol 2007 Sep 20;25(27):4210-6
• Bartella L et al.: "Enhancing nonmass lesions in the breast: evaluation with proton (1H) MR spectroscopy", Radiology. 2007 Oct;245(1):80-7
• Magnusson C et al.: "Cigarette smoking and breast cancer risk: a population-based study in Sweden", Br J Cancer. 2007 Oct 2; [Epub ahead of print]

Editorial / Editoriale

• "Quality of life is better in metastatic breast cancer women receiving chemotherapy than those under only supportive care" - Michalis V. Karamouzis, First Department of Medical Oncology, St. Savvas Anticancer-Oncologic Hospital, Athens, Greece
  
  "Breast cancer is the most common cancer diagnosed in women in Western countries. Many of these patients develop metastatic disease in the course of their illness. One of the goals of treating patients with metastatic breast carcinoma is to provide palliation and improve their quality of life. It is usually assumed that the number and severity of symptoms caused by the tumour will be decreased by chemotherapy, and that there is a direct relationship between the tumour load and its symptomatic effect on the patient. A few studies have shown that objective responses to chemotherapy are associated with improvement of various parameters of the quality of life of these patients. The aim of our study was to evaluate quality of life parameters in patients with metastatic breast carcinoma and assess the  differences between women receiving chemotherapy and those undergoing supportive care interventions. 210 patients with metastatic breast carcinoma were enrolled in this prospective, randomized, single-institution study. The primary outcome of the trial was quality of life assessment.. Quality of life was found to be statistically better in metastatic breast cancer women receiving chemotherapy than those under only supportive care. Statistically significant differences in favour of chemotherapy were also found in functioning subscales, symptom single-item questions and sexual functioning. Our findings suggest that chemotherapy in metastatic breast cancer women with good performance status represents the more rational therapeutic approach to quality of life improvement".
  (Comment on paper: Karamouzis MV et al.: "Quality of life in metastatic breast cancer patients under chemotherapy or supportive care: a single-institution comparative study", Eur J Cancer Care (Engl). 2007 Sep;16(5):433-8)

Original Articles / Articoli Originali

• "Ductal Carcinoma in situ: surgical therapy. A mini review" - Franceschini G et al., Unità Operativa di Chirurgia Senologica, Università Cattolica del Sacro Cuore - Policlinico Agostino Gemelli - Roma, Italy

Press Releases / Comunicati Stampa

• "Residual fetal cells in women may provide protection against breast cancer" - Fred Hutchinson Cancer Research Center, Seattle, WA, USA  - www.fhcrc.org
• "Microarray Provides Three Genomic Guides to Breast Cancer Treatment Decisions" - University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

News from Healthcare Companies / Notizie dalle Aziende

• "Herceptin eradicates tumours and may reduce the need for mastectomies in women with inflammatory HER2-positive breast cancer – one of the most aggressive and fastest growing forms of the disease" - Roche - www.roche.com

Calendar of Events / Prossimi Eventi Senologici

• 13th Annual Perspectives in Breast Cancer, Oct 5 - 6, 2007, Boston, MA, USA
• Convegno Nazionale GISMa 2007,  11-12 Ottobre 2007, Pescheria del Garda (VR), Italy
• Controversies in Breast Cancer Adjuvant and Neoadjuvant Therapy 2007, Oct 12 - 14, 2007, New York, NY, USA
• Advanced course of mastology, 17- 19 ottobre 2007, Bari, Italy
• Breast MRI International Course, October 27th 2007, Firenze, Italy
• Attualita' in Senologia, 29 - 31 ottobre 2007, Firenze, Italy
• Carcinoma della mammella: chirurgia e immagine corporea, 30 October, 2007, Firenze, Italy
• San Antonio Breast Cancer Symposium, December 13-16, 2007, San Antonio Convention Center, San Antonio, TX, USA

Literature Selection / Selezione della Letteratura

• Kim DH et al.: "CT colonography versus colonoscopy for the detection of advanced neoplasia", N Engl J Med. 2007 Oct 4;357(14):1403-12
• Hoffmeister M et al.: "Individual and joint use of statins and low-dose aspirin and risk of colorectal cancer: a population-based case-control study", Int J Cancer. 2007 Sep 15;121(6):1325-30
• Plummer M et al.: "Helicobacter pylori cytotoxin-associated genotype and gastric precancerous lesions", J Natl Cancer Inst. 2007 Sep 5;99(17):1328-34
• Cantini F et al.: "Isolated knee monoarthritis heralding resectable non small-cell lung cancer. A paraneoplastic syndrome not previously described", Ann Rheum Dis. 2007 Sep 3; [Epub ahead of print]
• Carlsson S et al.: "Anxiety associated with prostate cancer screening with special reference to men with a positive screening test (elevated PSA) - Results from a prospective, population-based, randomised study", Eur J Cancer. 2007 Sep;43(14):2109-2116
• Tahrini AA et al.: "Durable complete responses with high-dose bolus interleukin-2 in patients with metastatic melanoma who have experienced progression after biochemotherapy", J Clin Oncol. 2007 Sep 1;25(25):3802-7
• Rhodes LE et al.: "Five-year follow-up of a randomized, prospective trial of topical methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma", Arch Dermatol. 2007 Sep;143(9):1131-6
• Callahan MJ et al.: "Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction", J Clin Oncol. 2007 Sep 1;25(25):3985-90
• Carlsen K et al.: "Are cancer survivors at an increased risk for divorce? A Danish cohort study", Eur J Cancer. 2007 Sep;43(14):2093-9
• Serraino D et al.: "Risk of cancer following immunosuppression in organ transplant recipients and in HIV-positive individuals in southern Europe", Eur J Cancer. 2007 Sep;43(14):2117-23