Literature Selection / Selezione della Letteratura

• Del Turco MR et al.: "Full-field digital versus screen-film mammography: comparative accuracy in concurrent screening cohorts", AJR Am J Roentgenol. 2007 Oct;189(4):860-6
• Howard RA et al.: "Leukemia following breast cancer: an international population-based study of 376,825 women", Breast Cancer Res Treat. 2007 Nov;105(3):359-68
• Schouten van der Velden AP et al.: "Local recurrences after different treatment strategies for ductal carcinoma in situ of the breast: a population-based study in the East Netherlands", Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):703-10
• Intra M et al.: "Unnecessary axillary node dissections in the sentinel lymph node era", Eur J Cancer. 2007 Oct 9; [Epub ahead of print]
• Tuttle TM et al.: "Increasing Use of Contralateral Prophylactic Mastectomy for Breast Cancer Patients: A Trend Toward More Aggressive Surgical Treatment", J Clin Oncol. 2007 Oct 22; [Epub ahead of print]
• Scalliet PG et al.: "Breast cancer in elderly women: Can radiotherapy be omitted?", Eur J Cancer. 2007 Oct;43(15):2264-9
• Hayes DF et al.: "HER2 and response to paclitaxel in node-positive breast cancer", N Engl J Med. 2007 Oct 11;357(15):1496-506
• van der Hage JJ et al.: "Efficacy of adjuvant chemotherapy according to hormone receptor status in young patients with breast cancer: a pooled analysis", Breast Cancer Res. 2007 Oct 11;9(5):R70 [Epub ahead of print]
• Graham PH et al.: "Anastrozole for malignant and benign conditions: present applications and future therapeutic integrations", Expert Opin Pharmacother. 2007 Oct;8(14):2347-57
• Courneya KS et al.: "Effects of aerobic and resistance exercise in breast cancer patients receiving adjuvant chemotherapy: a multicenter randomized controlled trial", J Clin Oncol. 2007 Oct 1;25(28):4396-404
• Wingo PA et al.: "Oral Contraceptives and the Risk of Death From Breast Cancer", Obstet Gynecol. 2007 Oct;110(4):793-800
• Li CI et al.: "Relationship between Age Maximum Height Is Attained, Age at Menarche, and Age at First Full-Term Birth and Breast Cancer Risk", Cancer Epidemiol Biomarkers Prev. 2007 Oct;16(10):2144-9
• Parmigiani G et al.: "Validity of models for predicting BRCA1 and BRCA2 mutations", Ann Intern Med. 2007 Oct 2;147(7):441-50
• Zheng I et al.: "Accelerated bone resorption, due to dietary calcium deficiency, promotes breast cancer tumor growth in bone", Cancer Res. 2007 Oct 1;67(19):9542-8
• Mulligan AM et al.: "Insulin receptor is an independent predictor of a favorable outcome in early stage breast cancer", Breast Cancer Res Treat. 2007 Nov;106(1):39-47

Editorial / Editoriale

• "Routine use of postoperative chest wall and nodal irradiation in all T3pN0 breast cancer patients may not be required"  - John E. Mignano, Department of Radiation Oncology, Johns Hopkins Hospital, Baltimore, MD, USA
  
  "The work presented in this paper began in the early 1990’s.  At that time, T3pN0 breast cancer was considered stage III disease and post-mastectomy radiation treatment was routinely offered.  The topic of adjuvant radiotherapy for T3pN0 patients has been revisited on a number of occasions since the early 1990’s and continues to be recommended by the National Comprehensive Cancer Network, despite classification of these patients being downstaged to IIB disease.  Some early studies by other investigators have also suggested that patients with T3pN0 breast cancer who have undergone mastectomy yielding clear margins may also not benefit by adjuvant irradiation.  Our study is among the largest and has one of the longest follow-up periods.  Our results demonstrate that the rate of local recurrence and distant failure for T3pN0 patients is not substantially different from T2pN0 mastectomy patients, and as such, adjuvant radiation treatment need not be routinely recommended".
  (Comment on paper: Mignano JE et al.: "Local recurrence after mastectomy in patients with T3pN0 breast carcinoma treated without postoperative radiation therapy", Am J Clin Oncol. 2007 Oct;30(5):466-72)

Original Articles / Articoli Originali

• "Evoluzioni nel trattamento chirurgico del carcinoma mammario precoce: mini-review" - Franceschini G et al., Unità Operativa di Chirurgia Senologica, Università Cattolica del Sacro Cuore - Policlinico Agostino Gemelli - Roma

Abstract: "Il trattamento chirurgico dei tumori della mammella ha subito continui e profondi cambiamenti negli ultimi 30 anni.   La chirurgia conservativa ha progressivamente e definitivamente sostituito la mastectomia nel trattamento dei tumori in stadio iniziale. Associata alla radioterapia, essa è in grado di garantire alle pazienti le stesse percentuali di sopravvivenza globale e migliori risultati estetici con un accettabile rischio di recidiva locale.   La diffusione dei programmi di screening ed il perfezionamento delle indagini diagnostiche hanno portato ad un incremento della diagnosi dei tumori infraclinici ed all’elaborazione di sempre più accurate tecniche di localizzazione e trattamento dei tumori non palpabili.   La tecnica del linfonodo sentinella per i tumori in stadio iniziale ha permesso di evitare in casi selezionati la dissezione ascellare di principio senza rinunciare alle importanti informazioni prognostiche dei linfonodi loco-regionali.  L’introduzione della chirurgia oncoplastica, coniugando tecniche di chirurgia generale con quelle proprie della chirurgia plastica, ha consentito di superare il conflitto tra estensione della resezione chirurgica e risultato estetico finale contribuendo in maniera importante a migliorare la qualità di vita delle pazienti (...)".

Calendar of Events / Prossimi Eventi Senologici

• Translational Therapies in Breast Cancer, Nov 17, 2007, Dallas, TX, USA
• San Antonio Breast Cancer Symposium, December 13-16, 2007, San Antonio Convention Center, San Antonio, TX, USA

Literature Selection / Selezione della Letteratura

• Rizzo JD et al.: "American Society of Clinical Oncology/American Society of Hematology 2007 Clinical Practice Guideline Update on the Use of Epoetin and Darbepoetin", J Clin Oncol 2007 Oct 22; [Epub ahead of print]
• Prentice RL et al.: "Low-Fat Dietary Pattern and Cancer Incidence in the Women's Health Initiative Dietary Modification Randomized Controlled Trial", J Natl Cancer Inst. 2007 Oct 9; [Epub ahead of print]
• Naucler P et al.: "Human papillomavirus and Papanicolaou tests to screen for cervical cancer", N Engl J Med. 2007 Oct 18;357(16):1589-97
• Mayrand MH et al.: "Human papillomavirus DNA versus Papanicolaou screening tests for cervical cancer", N Engl J Med. 2007 Oct 18;357(16):1579-88
• Tsai HK et al.: "Androgen Deprivation Therapy for Localized Prostate Cancer and the Risk of Cardiovascular Mortality", J Natl Cancer Inst. 2007 Oct 9; [Epub ahead of print]
• Rosero-Bixby L et al.: "X-ray screening seems to reduce gastric cancer mortality by half in a community-controlled trial in Costa Rica", Br J Cancer. 2007 Oct 8;97(7):837-43
• Chen LB et al.: "(18)F-DG PET/CT in detection of recurrence and metastasis of colorectal cancer", World J Gastroenterol. 2007 Oct 7;13(37):5025-9
• Bandi G et al.: "Cryoablation of small renal masses: assessment of the outcome at one institution", BJU Int. 2007 Oct;100(4):798-801

Editorial / Editoriale

• "Computed tomographic colonography and optical colonoscopy for colorectal-cancer screening and prevention" - David H Kim,  Department of Radiology, University of Wisconsin Medical School, Madison, USA

"CT colonography is an effective method to screen for colorectal cancer equivalent to traditional colonoscopy.  CT colonography holds advantages over colonoscopy because it is less invasive, less costly and has a lower risk of complications.  The bottom line, however, is that both tests are needed to screen the large numbers of eligible people who currently are not evaluated by any method. There are many people that are dying needlessly for a largely preventable cancer" .
(Comment on paper: Kim DH et al.: "CT colonography versus colonoscopy for the detection of advanced neoplasia", N Engl J Med. 2007 Oct 4;357(14):1403-12)

Clinical Guidelines / Linee guida cliniche (link)

• "Intravesical microwave hyperthermia with intravesical chemotherapy for superficial bladder cancer: guidance" - NICE - National Institute For Clinical Excellence, London, UK, www.nice.org.uk

Video and Lectures / Conferenze e Video (link)

• Sleep Disorders in cancer patients - University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org

Literature Selection / Selezione della Letteratura

• Bachmann GA et al.: "Lowest Effective Transdermal 17{beta}-Estradiol Dose for Relief of Hot Flushes in Postmenopausal Women: A Randomized Controlled Trial", Obstet Gynecol. 2007 Oct;110(4):771-779
• Kingsberg S et al.: "Evaluation of the clinical relevance of benefits associated with transdermal testosterone treatment in postmenopausal women with hypoactive sexual desire disorder", J Sex Med. 2007;4(4 Pt 1):1001-8