Gian Paolo Andreoletti, MD, Editor-in-Chief  -  paolo.andreoletti@senology.it

Best Study of the Month

• He Q et al.: "A pilot study on thoracoscopic internal mammary lymphatic chain dissection for breast cancer", Breast. 2008 Dec;17(6):568-73

Vote for your favourite study

Literature Selection

• Orgeas CC et al.: "The influence of menstrual risk factors on tumor characteristics and survival in postmenopausal breast cancer", Breast Cancer Res. 2008 Dec 16;10(6):R107
• Gunter MJ et al.: "Insulin, Insulin-Like Growth Factor-I, and Risk of Breast Cancer in Postmenopausal Women", J Natl Cancer Inst. 2009 Jan 7;101(1):48-60
• Li Y et al.: "Wine, liquor, beer and risk of breast cancer in a large population", Eur J Cancer. 2008 Dec 16. [Epub ahead of print]
• Maruti SS et al.: "Folate and one-carbon metabolism nutrients from supplements and diet in relation to breast cancer risk", Am J Clin Nutr. 2008 Dec 30. [Epub ahead of print]
• Fejerman L et al.: "Genetic Ancestry and Risk of Breast Cancer among U.S. Latinas", Cancer Res. 2008 Dec 1;68(23):9723-8
• Ahern TP et al.: "Digoxin treatment is associated with an increased incidence of breast cancer: a population-based case-control study", Breast Cancer Res. 2008 Dec 3;10(6):R102
• Gold EB et al.: "Dietary Pattern Influences Breast Cancer Prognosis in Women Without Hot Flashes: The Women's Healthy Eating and Living Trial", J Clin Oncol. 2008 Dec 15. [Epub ahead of print]
• Sheu BC et al.: "Clinical significance of tumor-infiltrating lymphocytes in neoplastic progression and lymph node metastasis of human breast cancer", Breast. 2008 Dec;17(6):604-10
• Mauri D et al.: "Multiple-Treatments Meta-analysis of Chemotherapy and Targeted Therapies in Advanced Breast Cancer", J Natl Cancer Inst. 2008 Dec 17;100(24):1780-91
• Schwarz-Dose J et al.: "Monitoring Primary Systemic Therapy of Large and Locally Advanced Breast Cancer by Using Sequential Positron Emission Tomography Imaging With [18F]Fluorodeoxyglucose", J Clin Oncol. 2008 Dec 15. [Epub ahead of print]
• Wenz F et al.: "Early initiation of external beam radiotherapy (EBRT) may increase the risk of long-term toxicity in patients undergoing intraoperative radiotherapy (IORT) as a boost for breast cancer", Breast. 2008 Dec;17(6):617-22
• Valenzano Menada M et al.: "Evaluation of endometrial thickness in hormone receptor positive early stage breast cancer postmenopausal women switching from adjuvant tamoxifen treatment to anastrozole2, Breast. 2008 Dec;17(6):631-6

Comments

• "A novel endoscopic-assisted technique for skin-sparing mastectomy" - Ken-ichi Ito, Division of Breast and Endocrine Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Nagano, Japan
   
  "We described a novel endoscopic-assisted technique for skin-sparing mastectomy combined with sentinel node biopsy, followed by immediate breast reconstruction with mammary prosthesis. We think that this technique reduces surgical scarring and provides excellent cosmetic results without diminishing oncological safety, and that the technique is well accepted by the patients with early-stage breast cancer. We suppose that the procedure could be considered an alternative treatment option for patients who are not candidates for breast-conserving surgery  because of the presence of a widespread intraductal component or multiple tumours."
  (Comment on: K.I. Ito et al.: "Endoscopic-assisted skin-sparing mastectomy combined with sentinel node biopsy", ANZ Journal of Surgery, 2008,  78(10): 894-898)

Press Releases

• San Antonio Breast Cancer Symposium Press Releases - www.sabcs.org

• "Early Stage, HER2 Positive Breast Cancer Patients at Increased Risk of Recurrence" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA  - www.mdanderson.org

Calendar of Events

• Society of Breast Imaging – Applications and Interpretation of Breast MRI, January 17-18, 2009, Santa Monica, CA, USA
• Miami Breast Cancer Conference, March 4-7, 2009, Orlando, FL, USA
• 11th International Conference on Primary Therapy of Early Breast Cancer, March 11-14, 2009, St. Gallen, Switzerland
• 2nd Annual Africa Breast Cancer Conference, March 17-18, 2009, Cairo, Egypt 

Images

malignant phylloides tumor

Stefano Ciatto, - CSPO - Istituto Scientifico Prevenzione Oncologica, Florence, Italy

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Best Study of the Month

• Widmark A et al.: "Endocrine treatment, with or without radiotherapy, in locally advanced prostate cancer (SPCG-7/SFUO-3): an open randomised phase III trial", Lancet. 2008 Dec 15. [Epub ahead of print]

Vote for your favourite study

Literature Selection

• Botteri E et al.: "Smoking and Colorectal Cancer: A Meta-analysis", JAMA. 2008 Dec 17;300(23):2765-78
• Barone BB et al.: "Long-term All-Cause Mortality in Cancer Patients With Preexisting Diabetes Mellitus: A Systematic Review and Meta-analysis", JAMA. 2008 Dec 17;300(23):2754-64
• Nagamura T et al.: "Coffee consumption and the risk of oral, pharyngeal, and esophageal cancers in Japan: the Miyagi Cohort Study", Am J Epidemiol. 2008 Dec 15;168(12):1425-32
• Johnson JR et al.: "Menopausal hormone therapy and risk of colorectal cancer", Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):196-203
• Slotman BJ et al.: "Prophylactic Cranial Irradiation in Extensive Disease Small-Cell Lung Cancer: Short-Term Health-Related Quality of Life and Patient Reported Symptoms--Results of an International Phase III Randomized Controlled Trial by the EORTC Radiation Oncology and Lung Cancer Groups", J Clin Oncol. 2008 Dec 1. [Epub ahead of print]
• Panici PB et al.: "Systematic Pelvic Lymphadenectomy vs No Lymphadenectomy in Early-Stage Endometrial Carcinoma: Randomized Clinical Trial", J Natl Cancer Inst. 2008 Dec 3;100(23):1707-16
• Shikata K et al.: "Population-based prospective study of the combined influence of cigarette smoking and Helicobacter pylori infection on gastric cancer incidence: the Hisayama Study", Am J Epidemiol. 2008 Dec 15;168(12):1409-15
• Brignardello E et al.: "Ultrasound screening for thyroid carcinoma in childhood cancer survivors: a case series", J Clin Endocrinol Metab. 2008 Dec;93(12):4840-3