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Gian Paolo Andreoletti, MD, Editor-in-Chief - paolo.andreoletti@senology.it
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Best Study of the Month
Literature Selection
- de Jong D et al.: "Anaplastic large-cell lymphoma in women with breast implants", JAMA. 2008 Nov 5;300(17):2030-5
- Gronwald J et al.: "Early radiation exposures and BRCA1-associated breast cancer in young women from Poland", Breast Cancer Res Treat. 2008 Dec;112(3):581-4
- Chlebowski RT et al.: "Calcium Plus Vitamin D Supplementation and the Risk of Breast Cancer", J Natl Cancer Inst. 2008 Nov 11. [Epub ahead of print]
- Al-Allaq HA et al.: "Magnetic resonance imaging identifies multifocal and multicentric disease in breast cancer patients who are eligible for partial breast irradiation", Cancer. 2008 Nov 1;113(9):2408-14
- Uematsu T et al.: "Comparison of magnetic resonance imaging, multidetector row computed tomography, ultrasonography, and mammography for tumor extension of breast cancer", Breast Cancer Res Treat. 2008 Dec;112(3):461-74
- Zahl PH et al.: "The Natural History of Invasive Breast Cancers Detected by Screening Mammography", Arch Intern Med. 2008 Nov 24;168(21):2311-2316
- Caliskan M et al.: "Paget's disease of the breast: the experience of the European institute of oncology and review of the literature", Breast Cancer Res Treat. 2008 Dec;112(3):513-21
- Sirohi B et al.: "Platinum-based chemotherapy in triple-negative breast cancer", Ann Oncol. 2008 Nov;19(11):1847-52
- Hermelink K et al.: "Short-term effects of treatment-induced hormonal changes on cognitive function in breast cancer patients: results of a multicenter, prospective, longitudinal study", Cancer. 2008 Nov 1;113(9):2431-9
Comments
- "Skin
necrosis after partial breast irradiation" -
Edward R. Sauter, Steven Westgate, Janice Templemire,
Departments of Surgery and Radiology, Ellis
Fischel Cancer Center, Columbia, MO and Department of Surgery,
University of North Dakota, Grand Forks, ND, USA
"We recently reported on two women who developed skin necrosis after partial breast irradiation. Notably, both smoked before and after their radiation treatment. Partial breast irradiation is well tolerated in the vast majority of subjects who receive this treatment. Nonetheless, complications can occur, including seromas, fat necrosis and infections. Cavity distance > 7 mm from skin surface has been noted by some authors to affect cosmesis. This distance was 11 in the first and 5 mm in the second subject. Smoking is known to increase perioperative complications after breast implant reconstruction for cancer, and smokers are known to have more late normal tissue complications following whole breast radiotherapy for breast cancer. We therefore believe smoking may have contributed to the complication in these two women, and wonder if others have had similar experiences in women who smoked during their treatment. In the future, we will strongly encourage women who smoke to stop smoking prior to our initiation of partial breast irradiation"
(Comment on: Sauter ER et al.: "Skin necrosis in cigarette smokers receiving partial breast irradiation: two case reports", Cases J. 2008;1(1):230. [Epub ahead of print])
Press Releases
-
"Migraines Associated with Lower Risk of Breast Cancer" - Fred Hutchinson Cancer Research Center, Seattle, WA, USA - www.fhcrc.org
Images
Infiltrating lobular carcinoma
Stefano Ciatto, - CSPO - Istituto Scientifico Prevenzione Oncologica, Florence, Italy
Calendar of Events
- First International Inflammatory Breast Cancer Conference, December 5-7, 2008, Houston, TX, USA
- 31st Annual San Antonio Breast Cancer Symposium, December 10-14, 2008, San Antonio, TX, USA
Best Study of the Month
Literature Selection
- Nailuri SR et al.: "Risk of Venous Thromboembolism With the Angiogenesis Inhibitor Bevacizumab in Cancer Patients: A Meta-analysis", JAMA. 2008 Nov 19;300(19):2277-2285
- Belldegrun AS et al.: "Cancer-specific survival outcomes among patients treated during the cytokine era of kidney cancer (1989-2005): a benchmark for emerging targeted cancer therapies", Cancer. 2008 Nov 1;113(9):2457-63
- Haasbeek CJ et al.: "Long-term results of salvage radiotherapy for the treatment of recurrent cervical carcinoma after prior surgery", Radiother Oncol. 2008 Nov;89(2):197-204
- De Meerleer G et al.: "Salvage intensity-modulated radiotherapy for rising PSA after radical prostatectomy", Radiother Oncol. 2008 Nov;89(2):205-13
- Hamilton RJ et al.: "The influence of statin medications on prostate-specific antigen levels", J Natl Cancer Inst. 2008 Nov 5;100(21):1511-8
- Wilson DO et al.: "The Pittsburgh Lung Screening Study (PLuSS): outcomes within 3 years of a first computed tomography scan", Am J Respir Crit Care Med. 2008 Nov 1;178(9):956-61
Comments
- "Cytoreductive surgery and
intraperitoneal hyperthermic chemotherapy for peritoneal surface
disease from colorectal cancer"- Perry
Shen, Department
of General Surgery, Surgical Oncology Section, Medical Center
Boulevard, Wake Forest University School of Medicine,
Winston-Salem, NC, USA
"This paper demonstrates that in a single institution which performs both liver resection and cytoreductive surgery/intraperitoneal hyperthermic chemotherapy for metastatic colorectal cancer, clinical outcomes are not significantly different. Selected patients with peritoneal surface disease who undergo complete cytoreduction and intraperitoneal hyperthermic chemotherapy can achieve longterm survival with acceptable morbidity and mortality. However there are still challenges presenting to patients with peritoneal surface disease from colorectal cancer in regards to preoperative imaging and standaradization of technique, approach, and prognostic factors. Further research is indicated to determine the true efficacy of this multimodality approach to a very difficult clinical presentation"
(Comment on: Shen P et al.: "Peritoneal Surface Disease from Colorectal Cancer: Comparison with the Hepatic Metastases Surgical Paradigm in Optimally Resected Patients", Ann Surg Oncol. 2008. [Epub ahead of print]) - "Importance of cancer
surveillance after liver transplantation"
- Fredrik
Aberg, Transplantation
and Liver Surgery Clinic, Helsinki University Hospital,
Helsinki, Finland
"Our study compared the incidence of cancer after liver transplantion with national cancer incidence rates stratified by age, sex, and calendar time.The results show that liver transplant patients have a 2.6-fold cancer incidence in comparison with the general population. The most common cancer
types are nonmelanoma skin cancer and non-Hodgkin lymphoma. Male gender, young age, and the immediate posttransplant period present as risk factors for non-Hodgkin lymphoma, whereas old age and antibody induction therapy increase the risk for skin cancers. This study points out the importance of cancer surveillance after liver transplantation as well as the need for innovative immunosuppression strategies associated with less cancer risk"
(Comment on: Aberg F et al.: "Risk of malignant neoplasms after liver transplantation: a population-based study", Liver Transpl. 2008;14(10):1428-36)
Press Releases
- "NCCN Updates Guidelines for Colorectal Cancer" - National Comprehensive Cancer Network, USA - www.nccn.org
- "Proton Therapy and Concurrent Chemotherapy May Reduce Bone Marrow Toxicity in Advanced Lung Cancer Patients - First study to examine the benefits of proton therapy versus standard treatment for lung cancer" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org
- "Novel Four Drug Combination Proves Safe for Lung Cancer Treatment - Study first to combine two chemotherapies and two targeted therapies" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org
- "Gene Variations Alter Risk of Esophageal Cancer" - The University of Texas, M. D. Anderson Cancer Center, Houston, TX, USA - www.mdanderson.org
Clinical Guidelines
- "Metastatic spinal cord compression" - NICE - National Institute For Clinical Excellence, London, UK - www.nice.org.uk
- "Electrically-stimulated intravesical chemotherapy for superficial bladder " - NICE - National Institute For Clinical Excellence, London, UK - www.nice.org.uk
Literature Selection
- Zhang SM et al.: "Effect of combined folic acid, vitamin B6, and vitamin B12 on cancer risk in women: a randomized trial", JAMA. 2008 Nov 5;300(17):2012-21
- Davis SR et al.: "Testosterone for low libido in postmenopausal women not taking estrogen", N Engl J Med. 2008 Nov 6;359(19):2005-17
- Katz D et al.: "Beginning IVF Treatments After Age 30 Increases the Risk of Breast Cancer: Results of a Case-Control Study", Breast J. 2008 Nov, 14(6): 517-522
- Roche
- AstraZeneca
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