|

Literature Selection / Selezione
della Letteratura
Editorial /
Editoriale
"With
respect to the conclusions of our study, we should make a
distinction between patients treated in the past and patients of
the present. For patients treated in the 1970s/1980s we found
moderately increased risk of myocardial infarction, angina
pectoris and congestive heart failure in comparison with the
general female population in the Netherlands. Risk of heart
disease depended on the type of treatment received. In general,
irradiated patients experienced higher risk of cardiac disease
than patients who underwent surgery only. Speaking in absolute
numbers: if we would follow 1000 women from our study for 10 years,
we would have expected 215 cardiac events to occur (based on
incidence rates of the Dutch population) while we found 70 more
events among the irradiated breast cancer patients, a 33% increase
in risk. Our advice to women who had radiotherapy during the
"higher risk" years would be to control and/or treat any
existing cardiovascular risk factors, like high blood pressure,
diabetes mellitus, hypercholesterolemia, and of course, to stop
smoking.
We cannot simply translate the results of our study to the
treatment regimens of today's practice. Over the past years new
techniques have been developed to treat target volumes more
precisely and to spare normal tissues more effectively. With
"Intensity Modulated Radiotherapy" the target organ is
optimally irradiated by making use of varying intensity of
radiation, while the surrounding tissues will be spared. "Image
Guided Radiotherapy" enables us to depict the target organ
plus surrounding tissues directly. Whether treatment with modern
techniques will prevent all late cardiac toxicity, must be
evaluated in another 15 - 20 years." . (Comment on
paper:
Hooning
MJ et al.: "Long-term risk of cardiovascular disease in
10-year survivors of breast cancer", J
Natl Cancer Inst. 2007 Mar 7;99(5):365-75)
Clinical Guidelines / Linee guida cliniche (link)
Video and Lectures / Conferenze e Video (link)
Press Releases / Comunicati
stampa
Calendar of Events / Prossimi Eventi Senologici
- 31st
Annual Symposium of the American Society of Breast Disease -
April 12-14, 2007, San Francisco, CA, USA
- Seventh
Annual New Strategies in Breast Cancer Conference - Apr 13 - 14,
2007, Philadelphia, PA, USA
- 1st
Interconference Breast Cancer Meeting, 19-22 April, 2007,
Sarajevo - Bosnia and Herzegovina

Literature Selection / Selezione della
Letteratura
- Stattin
P et al.: "Prospective study of hyperglycemia and cancer
risk", Diabetes Care.
2007 Mar;30(3):561-7
- Bach
PB and al.: "Computed tomography screening and lung cancer
outcomes", JAMA.
2007 Mar 7;297(9):953-61
- New
York Early Lung Cancer Action Project Investigators: "CT
Screening for Lung Cancer: Diagnoses Resulting from the New York
Early Lung Cancer Action Project", Radiology
2007;243:239-249
- van
Meerbeeck JP et al.: "Randomized controlled trial of
resection versus radiotherapy after induction chemotherapy in
stage IIIA-N2 non-small-cell lung cancer", J
Natl Cancer Inst. 2007 Mar 21;99(6):442-50
- Austin
GL et al.: "A diet high in fruits and low in meats reduces
the risk of colorectal adenomas", J
Nutr. 2007 Apr;137(4):999-1004
- Rostom
A et al.: "Nonsteroidal Anti-inflammatory Drugs and
Cyclooxygenase-2 Inhibitors for Primary Prevention of Colorectal
Cancer: A Systematic Review Prepared for the U.S. Preventive
Services Task Force", Ann
Intern Med. 2007 Mar 6;146(5):376-89
- Lurie
G et al.: "Association of estrogen and progestin potency of
oral contraceptives with ovarian carcinoma risk", Obstet
Gynecol. 2007 Mar;109(3):597-607
- Bruno
B et al.: "A comparison of allografting with autografting
for newly diagnosed myeloma", N
Engl J Med. 2007 Mar 15;356(11):1110-20
- Aleman
BM et al.: "Late cardiotoxicity after treatment for Hodgkin
lymphoma", Blood. 2007 Mar
1;109(5):1878-86
- Bonnet
C et al.: "CHOP alone compared with CHOP plus radiotherapy
for localized aggressive lymphoma in elderly patients: a study
by the Groupe d'Etude des Lymphomes de l'Adulte", J
Clin Oncol. 2007 Mar 1;25(7):787-92
- Hijiya
N et al.: "Cumulative incidence of secondary neoplasms as a
first event after childhood acute lymphoblastic leukemia", JAMA.
2007 Mar 21;297(11):1207-15
- Tewari
A et al.: "Long-term survival in men with high grade
prostate cancer: a comparison between conservative treatment,
radiation therapy and radical prostatectomy - a propensity
scoring approach", J
Urol. 2007 Mar;177(3):911-5
- Marks
LS et al.: "PCA3 Molecular Urine Assay for Prostate Cancer
in Men Undergoing Repeat Biopsy", Urology.
2007 Mar;69(3):532-5
- International
Agency for Research on Cancer Working Group on artificial
ultraviolet (UV) light and skin cancer "The association of
use of sunbeds with cutaneous malignant melanoma and other skin
cancers: A systematic review", Int
J Cancer. 2007 Mar 1;120(5):1116-22
Video and Lectures / Conferenze e Video (link)
Press Releases / Comunicati
Stampa
Clinical Guidelines / Linee guida cliniche (link)
 Literature Selection / Selezione della
Letteratura
Visitate periodicamente le sezioni "Senology News /
Notizie flash in Senologia" e "Oncology
News / Notizie flash in Oncologia" per conoscere in maniera
tempestiva e concisa le novità internazionali in ambito senologico.ed oncologico
Accedete al Forum di
discussione per eventuali osservazioni, note o commenti.
|