28/06/2014

Positività dei margini chirurgici in pazienti con carcinoma lobulare in situ della mammella

"We reviewed 2358 patient records to assess the impact of the presence of Lobular Carcinoma In-Situ (LCIS) at the surgical margins after the final breast-conserving surgery on local control. All patients underwent lumpectomy and breast radiation. Our study did not find a statistically significant increase in loco-regional recurrence with the presence of LCIS-positive/close surgical margins in patients treated for invasive cancer with breast conserving surgery and radiation therapy. Therefore, our data suggest that LCIS-positive/close surgical margins after lumpectomy are not an indication for surgical re-excision or mastectomy”.
(Commentary on
Sadek BT et al.: "Risk of Local Failure in Breast Cancer Patients With Lobular Carcinoma In Situ at the Final Surgical Margins: Is Re-excision Necessary?", Int J Radiat Oncol Biol Phys. 2013 Sep 21[Epub ahead of print])

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