01/04/2014

Alcuni miRNA nel succo gastrico possono essere dei biomarkers per il tumore dello stomaco

"MicroRNAs (miRNAs) play crucial roles during carcinogenesis, but whether miRNAs in gastric juice, which is specific for gastric tissues, can be used as biomarkers of gastric cancer is largely unclear. Patients with gastric cancer had significantly different level of gastric juice miR-21 and miR -106a compared with patients with benign gastric diseases. The areas under ROC curves were up to 0.969 and 0.871 for miR-21 and miR -106a , respectively. Certain miRNAs including miR-21 and miR -106a in gastric juice can be used as biomarkers for the detecting of gastric cancer with a satisfactory specificity and sensitivity".

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