Changed cytokine patterns in the breast milk during inflammatory breast diseases and their side effects for the newborn


Despite a surge of evidence on the benefits of breastfeeding for mothers and the newborns there is a lack of valid and empirical data on lactation-related inflammatory breast diseases, which are also the most common reason for early weaning. Additionally there is also only little research on collateral effects of these puerperal diseases. But inflammatory breast diseases during lactation, like milk stasis or puerperal mastitis, cause a modulation of cytokine levels in breast milk. This imbalance of cytokines in breast milk may have severe consequences for the newborn, which in turn affects the child's development. In our systematic review all important studies and possible health effects for the childs are summarized with regard to different cytokines. Until now proceeding of breastfeeding is recommended also during theses inflammatory breast diseases, but we have to consider these side effects for the newborn in the future and need further investigations to analyze the correlations

 

 

 

Bibliographic Reference

Wockel A et al.: "Inflammatory breast diseases during lactation: health effects on the newborn-a literature review", Mediators Inflamm. 2008;2008:298760

 

 

Achim Wöckel

Department of Gynecology and Obstetrics, University Hospital Ulm, Ulm, Germany