Nonsteroidal anti-inflammatory drugs use is associated with reduced risk for breast cancer

The conclusions of our study are globally that regular use of any nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with a relative risk reduction for breast cancer of 12 percent  compared with non-users. A separate analysis for aspirin shows a 13 percent relative risk reduction, and an analysis for ibuprofen showed  a 21 percent relative reduction in risk for breast cancer. However, this does not mean  that we recommend the use of NSAIDs as a preventive measure as these  drugs may cause gastrointestinal bleeding

Bibliographic Reference

Takkouche B and al.: "Breast Cancer and Use of Nonsteroidal Anti-inflammatory Drugs: A Meta-analysis", J Natl Cancer Inst. 2008 Oct 7. [Epub ahead of print]

Bahi Takkouche
Department of of Preventive Medicine, University of Santiago de Compostela, Spain