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Previous use of carbonated soft drinks and esophageal or cardia adenocarcinoma
An ecological study reported a striking correlation between an increased use of carbonated soft drinks and the increasing incidence of adenocarcinoma of the esophagus in western societies, but in an analytical study from the United States no positive association was found. We conducted a large-scale nationwide population-based case-control study to evaluate the potential link between exposure to carbonated soft drinks and risk of esophageal adenocarcinoma. In total, we interviewed 189 patients with esophageal adenocarcinoma, 262 with cardia adenocarcinoma and 820 randomly selected population-based control participants. No association was found between previous use of carbonated soft drinks and later development of esophageal or cardia adenocarcinoma, independent of frequency or the duration of such use.The conclusion of the study was that no evidence of a link between carbonated soft drinks and esophageal adenocarcinoma was identified and thus such exposure should not cont ribute to the increasing incidence of this cancer.
Bibliographic reference:
Jesper Lagergren
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