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Importance
of
cancer surveillance after liver transplantation
Our study
compared the incidence of cancer after liver transplantion with
national cancer incidence rates stratified by age, sex, and calendar
time.
The results show that liver transplant patients have a 2.6-fold cancer
incidence in comparison with the general population. The most common
cancer
types are nonmelanoma skin cancer and non-Hodgkin lymphoma. Male gender,
young age, and the immediate posttransplant period present as risk
factors
for non-Hodgkin lymphoma, whereas old age and antibody induction therapy
increase the risk for skin cancers. This study points out the importance
of
cancer surveillance after liver transplantation as well as the need for
innovative immunosuppression strategies associated with less cancer
risk.
Bibliographic Reference
Aberg F et al.: "Risk of malignant neoplasms after liver transplantation: a
population-based study", Liver Transpl. 2008 Oct;14(10):1428-36
Fredrik Aberg
Transplantation and Liver
Surgery Clinic, Helsinki University Hospital, Helsinki, Finland
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