"Circadian disruption on breast cancer risk in women" - Sara Wagner Robb, Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA - "In our comprehensive analysis of 28 observational studies, we found that circadian disruption, including shift work, exposure to light at night, and employment as a flight attendant, was associated with an increased risk of breast cancer in women. Findings from this study should prompt future research to confirm the causal relationship between circadian disruption and breast cancer"
"Cadmium and breast cancer risk" - Loreta Strumylaite, Lithuanian University of Health Sciences, Kaunas, Lithuania - The data of a case-control study support cadmium as a risk factor for breast cancer, especially for both ER+ and HER2- cancer patients. There is evidence that cadmium may contribute to the cause of breast cancer acting as metalloestrogens via estrogen receptor (ER) and/or directly transforming normal human breast epithelial cells into a basal-like cancer phenotypecharacterized by negative human epidermal growth factor receptor 2 (HER2).
"Whole breast proton irradiation in women with breast cancer" - Mirjam Mast, Radiotherapy Centre West, The Hague, The Netherlands - "When using radiotherapy for left-sided breast cancer a breath-hold technique can be used to decrease the dose in the heart. However, due to anatomical variations in some patients, the radiation dose to the heart remains relatively high, even with the use of advanced photon-based techniques. In a radiotherapy planning study, in which 20 left-sided breast cancer patients were included, we noted that intensity modulated proton therapy (IMPT), when compared to intensity modulated radiotherapy (IMRT; i.e. photon therapy), enabled better sparing of the heart, even without using a breath-hold technique"