"Circadian disruption on breast cancer risk in women" - Sara Wagner Robb, Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, GA, USA - "In our comprehensive analysis of 28 observational studies, we found that circadian disruption, including shift work, exposure to light at night, and employment as a flight attendant, was associated with an increased risk of breast cancer in women. Findings from this study should prompt future research to confirm the causal relationship between circadian disruption and breast cancer"
"Whole breast proton irradiation in women with breast cancer" - Mirjam Mast, Radiotherapy Centre West, The Hague, The Netherlands - "When using radiotherapy for left-sided breast cancer a breath-hold technique can be used to decrease the dose in the heart. However, due to anatomical variations in some patients, the radiation dose to the heart remains relatively high, even with the use of advanced photon-based techniques. In a radiotherapy planning study, in which 20 left-sided breast cancer patients were included, we noted that intensity modulated proton therapy (IMPT), when compared to intensity modulated radiotherapy (IMRT; i.e. photon therapy), enabled better sparing of the heart, even without using a breath-hold technique"
"Timing of breast reconstruction and radiotherapy in women with breast cancer", Liesbeth Boersma, Maastricht University Medical Center, Department of Radiation Oncology, Maastricht, The Netherlands: "Effect of timing of breast reconstruction and radiotherapy (RT), with respect to complications and cosmetic outcomes: a) An implant reconstruction prior to postmastectomy RT yields less complications than after RT; b) Timing of RT has no impact on severe complication rate in case of an autologous reconstruction; c) Autologous reconstruction prior to RT yields more fibrosis than reconstruction after RT; d) Attention should be focused on reporting using standardized outcome measures"